Requirement of Intact Adenosine A1 Receptors for the Diuretic and Natriuretic Action of the Methylxanthines Theophylline and Caffeine

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This article is study that shows how A1 adenosine receptors are needed for the diuretic and natriuertic effects of methylxanthines such as theophylline and caffeine. The blockade of these receptors caused by the mentioned substances causes diuresis and natriuresis.

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To quote this article in bibliography using Chicago style :

Rieg, Timo, Hannah Steigele, Jurgen Schnermann, Kerstin Richter, Hartmut Osswald and Volker Vallon. “ Intact Adenosine A1 Receptors for the Diuretic and Natriuretic Action of the Methylxanthines Theophylline and Caffeine." Journal of Pharmacology and Experimental Therapeutics 313, no. 1 (2005): 403-409. https://doi.org/10.1124/jpet.104.080432.

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