RE: Is depression an exaggeration of body's healing mechanisms - Taking a dive into depression and inflammation.

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I recently read about depression contributing to pain but I have not yet heard about pain / inflammation contributing to depression.

For clarity, I am referring to clinical depression in the former case, not what we in our colloquial may refer to as being depressed or sad. (Although, my pain can prompt such feelings)

I'm going to review this more closely but based on the premise as I understand, I need to make sure to stay on top of taking my anti-inflammatory medications and / or more holistic remedies to assist my body in healing.

Caveat: I understand there may be issues with NSAIDs so would highly recommend people looking into remedies such as Tumeric.



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I think it's more likely that they both fuel each other. I mentioned one such possibility in the article such as inflammation-Dopamine accumulation-ROS generation-more inflammation pathway. Similar axis could also exist for cell damage caused by depression. Then there can be behaviour alteration, where poor lifestyle habits may fuel further inflammation.

I have heard of reports on depression altering pain perception. However, there are also reports on pain-sensing neurons being able to turn on the inflammatory response (I did a small post on this). Though at the moment I am not aware of the nociceptor-inflammation-depression axis. Something that should be looked into, however.

Ah! Turmeric. I remember as a child, having to drink a glass full of turmeric dissolved in hot milk. I would get that every time I would get wounded while playing. Quite recently someone gave it to me the last time I caught a common cold. I was fine the next morning, though hard to say if it was meds or if it was the yellow latte. I find this suggestion of turmeric very interesting and would love to explore the possibility.

Thanks for for your insightful comment, I have a lot more questions in mind now. If you happen to find something interesting during your review, please share. :)

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