RE: Is anti-viral interferon response a boon to SARS-CoV-2?

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It is a very violent virus and easy to spread, perhaps preventive measures will help a little but not completely, sometimes it is inevitable not to get infected, now how close are we to being able to get a vaccine soon? I was reading that a group of scientists at Oxford University are very close to finding a vaccine, I ask you because I know you are in Europe and you are working with this. Unfortunately in our country we can't do much even though we have excellent professionals in the area of virology



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That's a good question but also a difficult one to answer. I can't tell you when, but I can tell you that there is a lot going on for it. The trials are being conducted for something as novel as RNA vaccines. There are a few groups who have developed monoclonal antibodies against the virus and some more who are still in process. There are others who have claimed some success with inactivated virus in rats and macaques. But that's the thing most of it is in early development or early human trial. Even the Oxford one was tested to work in macaques. They are running phase 1 trials now. You can read this to see current state of some efforts.

Now the phase 1 trial will mostly test the safety and immunogenic potential (ability to mount immune response and produce antibodies) in small group. We have to wait at least until phase 3 to be sure if vaccine is both safe and effective against the virus. Some of these efforts would leas nowhere. Those that do may take at least a year (that is most hopeful scenario) to two (more realistic though still bit wishful scenario). If everything works out just fine, the approvals are accelerated then 1-2 years is wishful but doable. That is what I think is the scene.

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Hello thank you for responding, I am aware that some tests are already being conducted and I am also aware that it takes a long time to find the right antidote, there are many tests, many phases, but I read in an article that they are already testing on people ... this is true ... I honestly do not think so and even more so for what you just told me, that maybe in a year we can have the vaccine.

Thank you for your answer and I apologize that I respond so late, my work is currently very demanding and I have little free time, which is why I enter very little stemsocial

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Quite the same here. I hope to write and read posts every evening, but by the time I finish work I am always too late and tired to anything useful.

Yes, a year is wishful thinking for sure. But deep down I do hope that I am wrong and wishful thinking turns into reality.

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