New variants of SARS-CoV-2

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Since human beings began to be infected by viruses, we also began to look for ways to counteract the undesirable effects of these infections.
As a consequence of these protection mechanisms, the molecular structures of viruses began to mutate, developing new mechanisms to gain entry into our cells. This phenomenon is called "mutation."

When a virus enters our cells, it begins to replicate and frequent changes occur in some of the amino acids that make up the virus proteins. As a consequence, the molecular structure is altered, and with it the properties of the virus.


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New variants of SARS-CoV-2

Currently, new versions of the virus are appearing. This is because at the beginning there were no methods to combat it, we were more susceptible, therefore, the transmission occurred in its native form.

Today, many people have already passed the infection and have antibodies against the virus. The use of allows to avoid contagions with good ventilation, and a global vaccination process has also begun.

These protection measures have caused changes (mutations) in the molecular structure of the virus, one of which is the increase in its ability to interact with the cell receptor.

The variants of SARS-CoV-2 that are worrying scientists, due to their speed of transmission, are the Brazilian, the South African and the British.

One of these mutations consists of a change in the structure that allows binding to the cell receptor, therefore contagion is faster and the spread can be greater, in addition to favoring binding to the receptor, it could make the virus more resistant to antibodies, thus increasing reinfections or decreasing the effectiveness of vaccines.

These variants can favor the spread in non-human species, which would allow the appearance of new strains that are more dangerous for people.


Conclusion

As new variants of the virus continue to emerge, there will be a greater number of infections and consequently, a greater number of victims.

Elderly people would be the most vulnerable because their bodies have less production of antibodies that are our natural protection, although all, in general, are susceptible to contagion and it is increasingly difficult to treat the sick.

The circulation of these variants will also affect the efficacy of vaccines and the frequency of reinfections,

Most of the studies have been carried out in in-vitro tests, which do not take into account the complex immune response that is generated in an organism. By confirming the lower effectiveness of the vaccines on these variants, it would imply that the vaccines would have to be updated based on the appearance of new strains, which would slow down the immunization process at a global level.

For all the above, we can assume that we still have a long way to go in this process of fighting the virus and humanity will have to continue modifying their daily routines of life in order to achieve survival.


@juanmolina


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10 comments
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Hello @juanmolina

As new variants of the virus continue to emerge, there will be a greater number of infections and consequently, a greater number of victims.

Correct, and precisely this alarming situation has been triggered by ourselves, and I say we, to refer to the world society, since the greater the number of infections the strains tend to present a higher degree of pathogenicity, and therefore can reach greater virulence. The opposite would have happened if the isolation and quarantine methods had been respected, since in cases where there is no host the virus weakens or in other words becomes less aggressive. Unfortunately, the situation may worsen in the following months. Best regards, be well.

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In my opinion, the virus will be overcome once our organisms manage to generate antibodies naturally. Unfortunately for this to happen we must be infected and not all of us have the necessary resistance. Therefore there will be more deaths. It is a very worrying dilemma.

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Hello friend, the truth is that this virus has taken us all by surprise and today there is talk about its mutations, it is a difficult situation because as you say it worsens the whole picture and the vaccine that is already established would be useless. I think it is a very difficult situation for the health profession and also people do not do their part, they do not take care of themselves or others, so it is much more difficult to fight any disease. Greetings!

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More than 400 health professionals have already died in our country.
Especially in Táchira the situation is at extreme levels in the infection rate. Hopefully there is no spread to the rest of the territory.

God protect us.

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Hello my friend @juanmolina,
Very explicit information that we comportes, it is certainly alarming the situation that is occurring as a result of the convid-19, but more alarming is the future that is looming because of the mutations that is presenting at the structural level this virus. The sad thing of all is that young people do not seem to care about what is happening and the countless victims who have lost the battle, and isolation and social distancing are not enough. Thank you for your contribution

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Despite suffering so many hardships daily, we Venezuelans cannot lower our guard against the covid.
More than 400 health professionals have already died in our country.
Especially in Táchira the situation is at extreme levels in the infection rate. Hopefully there is no spread to the rest of the territory.

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One of the things that personally strikes me is that the new strains are in countries where the economies are in trouble, although I do not doubt the mortality of the virus, the sad reality of my country is that the virus in the least of our problems, hunger and diseases such as malaria are killing more people than the virus.

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... the sad reality of my country is that the virus in the least of our problems

Sadly you are right.
But the covid could finish annihilating us.

Do you know why it has not spread more violently in Venezuela?
Because Venezuelans do not have the possibility to move as we did before. Currently, a simple trip from one state to another carries expenses that many cannot cover. In addition to the gasoline shortages.

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