"Identify the molecule" league #33. Prize: knowledge + 5 Hive + 100 STEM + 100 CCC + 100 PAL + 200 TMN

in STEMGeeks2 months ago (edited)

This contest is an attempt to promote scientific knowledge among community in a fun and interesting way with the help of molecules.
Some people like to travel around the world and tell others stories about what happens outside of our organisms/cells in other countries.
And with “Identify the molecule” contest you can try to travel inside our own organism/cells and cells of the organisms around us.

Important
In order to get TMN, you’ll need to have NEO-wallet and provide me your public NEO-address.
If you don’t have it yet, don’t worry, I published a post on how/where to get it (O3 wallet).
Note that NEO-addresses provided by exchanges will not work in this case (+ it's safer NOT to keep your funds on exchanges). It's highly recommended to get O3 wallet.

For more information about this contest and its rules (especially if you're new to it) read

"Identify the molecule" contest. Upgrade (the league, additional bonuses and more)

and

"Identify the molecule" league #30. Prize: knowledge + 5 Hive + 100 STEM + 100 CCC + 100 PAL + 200 TMN

If there’re no winners on any stage, the bonuses will be distributed equally among all users who provided any guesses for molecules.


Riddle

riddle_33_33_.png

(Public domain, from Wikipedia. The molecule was added by me (see below))

Today's molecule is an enzyme which takes part in heme biosynthesis.

riddle_33_cartoon.png

(Cartoon representation. You can see the molecule together with its substrate on the image above. The image was created by me with the help of PyMol - open source tool for molecular visualization/exploration. PDB-file was obtained from PDB)

In some cases (less than 1 in 1,000,000), mutations of this molecule’s gene happen, which leads to a condition (due to accumulation of abnormal toxic substrates) with a number of symptoms like:
photosensitivity (hence, skin wounds)
red urine
fluorescent teeth
thick skin and short peripheral phalanges of the fingers (“werewolf hands”)
erythrodontia (teeth become reddish)
desire to drink blood
hypertrichosis (excess amount of hair) on the limbs, back, and face (”werewolf syndrome”)
anemia (hence, weariness and pallor)

So, the whole vampires/werewolf phenomenon in our culture most likely could be explained by the deficiency of this molecule.

nosferatu1639125_1280.png
(source - Pixabay. Thanks to Pixaline)

riddle_33_surface.png

(Surface representation. You can see the molecule together with its substrate on the image above. The image was created by me with the help of PyMol - open source tool for molecular visualization/exploration. PDB-file was obtained from PDB)

"Edited"
The number of letters in the molecule's name with some of them presented goes below:
riddle_cells.png

Rules

This contest lasts for 6 days.

Leave your guess (1 guess only (not 2 or 3+)) in the comments section of the post.

Don’t edit your comment/Don't delete or add new comments with the answers and don’t provide any evidence that your answer is correct.

The first user with correct answer is the winner.

Some of the clues have already been provided in the post.

Additional clues will be given Wednesday (20:00 ± 15 minutes UTC) (I’ll update this post).

The reason is that some people might need less information to make conclusions that the others.

Additional clues will be added at the end of the "Riddle" section before the "Rules" section with "Edited" label.

The winner will be announced on Friday, August 14, 2020, 20:00 ± 15 minutes UTC in the comments section of the next post. Plus I’ll publish a detailed review of the riddle after a while.

I’ll transfer the tokens (STEM + Hive + TMN + CCC + PAL) (if the winner provides me his/her NEO-address) to the winner on that day and add the transaction ID in the comments section.

I’m planning to run this contest every week.
So, you should expect to see the 3rd week’s riddle for August on Saturday, August 15, 2020, 20:00 ± 15 minutes UTC.

References

I’ll add all the references for this post later, because most of them contain the name of the molecule.
That would be a spoiler.
I’ll add them after a while.

Important

This contest is the work in progress.
A lot can be changed in the future.
Any recommendations/suggestions are very welcome.
If you have any questions, feel free to ask them in the comments section.

All images (without the license specified) are used under the doctrine known in USA as "Fair Use" (similar doctrines are used in other countries). For more information visit the US Gov website

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Uroporphyrinogen III synthase

you're right.
just sent everything.
5 Hive
https://peakd.com/@alexbiojs/wallet

100 STEM, and 100 Pal and 100 CCC
https://he.dtools.dev/@alexbiojs

200 TMN

https://neoscan.io/transaction/80ed7d007eff3d19491b5d8efa1af0b104771ba0d25d429b66de62cc5123e2c5

thanks for your interest for this contest )

Uroporphyrinogen

hi
Uroporphyrinogen III synthase is the right answer
you were close.
To encourage people to participate in the contest,
I changed the rules a little,
From now on, everyone who participated in the contest/provided some guesses for molecules,
will get 100 PAL, 100 CCC and 20 STEM
just sent them
https://he.dtools.dev/@alexbiojs

thanks for your interest )