"Identify the molecule" league #31. Molecule of the month (July). Prize: knowledge + 10 Hive + 200 STEM + 200 CCC + 200 PAL + 400 TMN

in STEMGeeks3 months ago (edited)

This contest is an attempt to promote scientific knowledge among community in a fun and interesting way with the help of molecules.
Some people like to travel around the world and tell others stories about what happens outside of our organisms/cells in other countries.
And with “Identify the molecule” contest you can try to travel inside our own organism/cells and cells of the organisms around us.

For more information about this contest read "Identify the molecule" contest. Upgrade (the league, additional bonuses and more) post.

Prizes/bonuses:

The prize here is

1. knowledge

facts, information, and skills acquired through experience or education; the theoretical or practical understanding of a subject
[Oxford Dictionary of English, 3rd Edition, Oxford University Press, 2010]

That understanding of our own organism and organisms around us is the real prize in the case of this contest. No matter what happens (whether or not you get 100 STEM), you can win (can acquire the knowledge by investigating different sources of information, remembering and using it to your advantage in the future).

2. 5 Hive

3. 100 STEM

STEMGeeks is a community focused on STEM topics rewarding engagement with STEM tokens. STEMGeeks is powered by the Steem blockchain with it's own distribution model for STEM tokens in addition to the potential STEEM tokens.
STEM stands for Science, Technology, Engineering, Math and includes a wide range of science and technology topics.
[source]

4. 100 CCC (CreativeCoin)

This is to bring the artistic community together and reward them with tokens for their work.
source

5. 100 PAL (PALcoin)
https://www.palnet.io/

6. 200 TMN

Aside from STEM I’d like to add TMN tokens.
For the uninitiated, TMN is the token of TranslateMe project (it’s about combining blockchain technology (NEO in this case) with translation industry).
The reason I’m going to add this token for the prize pool of this contest is not only because I have them, but because this contest is quite scientific, and TranslateMe project might help to solve the “lost” science problem.
For more on this you can read my post regarding TranslateMe (TranslateMe (or Decentralization meets Translation industry). Part 2. The “missing puzzle piece” of scientific ecosystem. General overview) (and other posts of that series (TranslateMe (or Decentralization meets Translation industry). Part 1. TranslateMe Chat App. Help to preserve languages, break language barriers, earn TMN. Twitter campaign (100 TMN bonus) and TranslateMe (or Decentralization meets Translation industry). Introduction)).

For more information on crypto-bonuses for this league, please refer to "Identify the molecule" contest. Upgrade (the league, additional bonuses and more) post.

Consider these tokens as a bonus.

Images and text are the clues for you to guess a riddle (the name of the molecule in this case).

Note that

a) even though this contest is called “Identify the molecule”,
-> molecule (singular)
sometimes it’s not just a molecule which is responsible for a specific function, but rather a complex of molecules.
Example:
cytochrome c oxidase (Complex IV)

is a large transmembrane protein complex… It is the last enzyme in the respiratory electron transport chain of cells located in the membrane.
source

b) some molecules/complexes have different names. For example, other names for cytochrome c oxidase (example above) are

Complex IV (mitochondrial electron transport).
Cytochrome a3.
Cytochrome aa3.
Cytochrome oxidase.
Warburg's respiratory enzyme.
source

Any of those names would be a valid entry.

c) Some almost identical molecules are grouped into classes / groups / families.
Example:
Helicases are divided into 6 groups. RecD and Dda molecules belong to helicases group (Superfamily 1 (SF1)). In this case you would need to guess only the name of the group –> Helicase/ Helicases.

d) Some proteins can have different forms – isoforms.
Example:
There’re trypsin 1 and trypsin 2. In this case you would need to guess only the general name – trypsin.


Important

In order to get TMN, you’ll need to have NEO-wallet and provide me your public NEO-address.
If you don’t have it yet, don’t worry, I published a post on how/where to get it (O3 wallet).
Note that NEO-addresses provided by exchanges will not work in this case (+ it's safer NOT to keep your funds on exchanges). It's highly recommended to get O3 wallet.

If there’re no winners on any stage, the prize will be distributed equally among all users who provided any guesses for molecules.


Riddle

Today’s riddle is about a group of molecules. It’s enough to guess just the name of the group.
The members are a subclass of the esterases and are present in a wide range of organisms: from fungi to people, from wasps and bees to viruses. And they can be found as inside the cells, as in the extracellular spaces in a wide range of tissues.

riddle_31_surface.png

(Surface representation. The image was created by me with the help of PyMol - open source tool for molecular visualization/exploration. PDB-file was obtained from PDB)

The molecules (the lack thereof) most likely would be one of the possible explanations for the appearance the majority of the people in “Wall-e” have.

The molecules are considered as one of the most important group in today’s biotechnology due to a number of characteristics, one of which it the ability to catalyse reactions in water soluble and water insoluble systems. And they can catalyse a number of reactions including hydrolysis, esterification, alcoholysis, which makes them great candidates for application in a number of industries like detergent, food, textile, pharmaceutical, cosmetics, and paper industries.

riddle_31_cartoon.png

(Cartoon representation. The image was created by me with the help of PyMol - open source tool for molecular visualization/exploration. PDB-file was obtained from PDB)

Here’s the data showing where (in what human normal tissues) the gene of the molecule (just for one of the members of the group) is expressed the most:

riddle_31_gene_expression.png

(in other words, those are the places where the molecule is present in abundance). The data were obtained with the help of Metabolic gEne RApid Visualizer

"Edited"

In English the molecule’s name consists of 6 letters (with “p” being the 3rd one):

riddle_31_cells.png

Rules

This contest lasts for 6 days.

Leave your guess (1 guess only (not 2 or 3+)) in the comments section of the post.

Don’t edit your comment/Don't delete or add new comments with the answers and don’t provide any evidence that your answer is correct.

The first user with correct answer is the winner.

Some of the clues have already been provided in the post.

Additional clues will be given Wednesday (20:00 ± 15 minutes UTC) (I’ll update this post).

The reason is that some people might need less information to make conclusions that the others.

Additional clues will be added at the end of the "Riddle" section before the "Rules" section with "Edited" label.

The winner will be announced on Friday, July 31, 2020, 20:00 ± 15 minutes UTC in the comments section of the next post. Plus I’ll publish a detailed review of the riddle after a while.

I’ll transfer the tokens (STEM + Hive + TMN + CCC + PAL) (if the winner provides me his/her NEO-address) to the winner on that day and add the transaction ID in the comments section.

I’m planning to run this contest every week.
So, you should expect to see the 1st week’s riddle for August on Saturday, August 1, 2020, 20:00 ± 15 minutes UTC.

Edited: The next stage is the Year's stage. Some big prizes are coming...

References

I’ll add all the references for this post later, because most of them contain the name of the molecule.
That would be a spoiler.
I’ll add them after a while.

Important

This contest is the work in progress.
A lot can be changed in the future.
Any recommendations/suggestions are very welcome.
If you have any questions, feel free to ask them in the comments section.

All images (without the license specified) are used under the doctrine known in USA as "Fair Use" (similar doctrines are used in other countries). For more information visit the US Gov website

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Lipase!

you're right.
congrats!

just sent you 200 STEM, 200 CCC, 200 PAL & 10 Hive

https://he.dtools.dev/@alexbiojs
https://peakd.com/@alexbiojs/wallet

and 400 TMN
https://neoscan.io/transaction/a3c07a3e1c90e0642dfcba1331ffa5af7a45e9850f45cefcc67e90807918c1dc

WHat's more, you were the winner for the week's stage here for July.
https://peakd.com/hive-163521/@alexbiojs/identify-the-molecule-league-30-prize-knowledge-5-hive-100-stem-100-ccc-100-pal-200-tmn
(Transcortin)
And winning the month's stage now makes you eligible for the Year's stage along with other 3 users.
which will happen at the end of August/ beginning of September.

Wow!! Thank you very much :) :)

!discovery 20


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