"Identify the molecule" league #26. Molecule of the month (May) (rules updated). Prize: knowledge + 10 Hive + 200 STEM + 200 CCC + 200 PAL + 400 TMN

in STEMGeeks4 months ago (edited)

The rules were updated a little bit. I don't see a reason to provide clues in 3 steps (Saturday, Monday and Wednesday).
I guess I'd be enough to provide the clues just 2 times (Saturday and Wednesday). So, you will see the next clues for today's riddle on Wednesday, May 27. And I added more bonuses

This contest is an attempt to promote scientific knowledge among community in a fun and interesting way with the help of molecules.
Some people like to travel around the world and tell others stories about what happens outside of our organisms/cells in other countries.
And with “Identify the molecule” contest you can try to travel inside our own organism/cells and cells of the organisms around us.

For more information about this contest read "Identify the molecule" contest. Upgrade (the league, additional bonuses and more) post.

Prizes/bonuses:

The prize here is

1. knowledge

facts, information, and skills acquired through experience or education; the theoretical or practical understanding of a subject
[Oxford Dictionary of English, 3rd Edition, Oxford University Press, 2010]

That understanding of our own organism and organisms around us is the real prize in the case of this contest. No matter what happens (whether or not you get 100 STEM), you can win (can acquire the knowledge by investigating different sources of information, remembering and using it to your advantage in the future).

2. 5 Hive

3. 100 STEM

STEMGeeks is a community focused on STEM topics rewarding engagement with STEM tokens. STEMGeeks is powered by the Steem blockchain with it's own distribution model for STEM tokens in addition to the potential STEEM tokens.
STEM stands for Science, Technology, Engineering, Math and includes a wide range of science and technology topics.
[source]

4. 100 CCC (CreativeCoin)

This is to bring the artistic community together and reward them with tokens for their work.
source

5. 100 PAL (PALcoin)
https://www.palnet.io/

6. 200 TMN

Aside from STEM I’d like to add TMN tokens.
For the uninitiated, TMN is the token of TranslateMe project (it’s about combining blockchain technology (NEO in this case) with translation industry).
The reason I’m going to add this token for the prize pool of this contest is not only because I have them, but because this contest is quite scientific, and TranslateMe project might help to solve the “lost” science problem.
For more on this you can read my post regarding TranslateMe (TranslateMe (or Decentralization meets Translation industry). Part 2. The “missing puzzle piece” of scientific ecosystem. General overview) (and other posts of that series (TranslateMe (or Decentralization meets Translation industry). Part 1. TranslateMe Chat App. Help to preserve languages, break language barriers, earn TMN. Twitter campaign (100 TMN bonus) and TranslateMe (or Decentralization meets Translation industry). Introduction)).

For more information on crypto-bonuses for this league, please refer to "Identify the molecule" contest. Upgrade (the league, additional bonuses and more) post.

Consider these tokens as a bonus.

Images and text are the clues for you to guess a riddle (the name of the molecule in this case).

Note that

a) even though this contest is called “Identify the molecule”,
-> molecule (singular)
sometimes it’s not just a molecule which is responsible for a specific function, but rather a complex of molecules.
Example:
cytochrome c oxidase (Complex IV)

is a large transmembrane protein complex… It is the last enzyme in the respiratory electron transport chain of cells located in the membrane.
source

b) some molecules/complexes have different names. For example, other names for cytochrome c oxidase (example above) are

Complex IV (mitochondrial electron transport).
Cytochrome a3.
Cytochrome aa3.
Cytochrome oxidase.
Warburg's respiratory enzyme.
source

Any of those names would be a valid entry.

c) Some almost identical molecules are grouped into classes / groups / families.
Example:
Helicases are divided into 6 groups. RecD and Dda molecules belong to helicases group (Superfamily 1 (SF1)). In this case you would need to guess only the name of the group –> Helicase/ Helicases.

d) Some proteins can have different forms – isoforms.
Example:
There’re trypsin 1 and trypsin 2. In this case you would need to guess only the general name – trypsin.


Important

In order to get TMN, you’ll need to have NEO-wallet and provide me your public NEO-address.
If you don’t have it yet, don’t worry, I published a post on how/where to get it (O3 wallet).
Note that NEO-addresses provided by exchanges will not work in this case (+ it's safer NOT to keep your funds on exchanges). It's highly recommended to get O3 wallet.

If there’re no winners on any stage, the prize will be distributed equally among all users who provided any guesses for molecules.


Riddle

Today's molecule has been studied for near 4 decades.
It's a glycoprotein and it exists as a part (and is a major protein component) of the extracellular matrix or plasma (produced by hepatocytes in this case).
It's quite popular molecule, and even some children at schools know about it when they study vascular system / blood at biology lessons.
cartton.png
(Cartoon representation. Note that there's just a part of the molecule on the image above (I didn't find PDB-file for the whole molecule). The image was created by me with the help of PyMol - open source tool for molecular visualization/exploration. PDB-file was obtained from PDB)

In English the molecule’s name consists of 11 letters (with “r” and “n” being the 4th and 6th correspondingly).

letters_little.png
(the image was created by me)

The molecule plays important role in our life, especially for those people involved in extreme/risky physical activities like stuntmans
(think of Jackie Chan)
https://www.erienewsnow.com/story/40220636/ultimate-list-of-jackie-chans-most-painful-injuries-and-broken-bones?clienttype=mobile
(Ultimate List Of Jackie Chan’s Most Painful Injuries And Broken Bones)
http://www.wearecallidus.com/opinion/jackie-chan/
(Jackie Chan: A catalogue of pain)
640pxJackie_Chan_2002.jpg
(Public Domain)

As you will see, the molecule is expressed by multiple cells (which should not be a surprise given that it's a part of the extracellular matrix)
I'd like you pay attention to the skin

Here’s the data showing where (in what human normal tissues) the gene of this molecule is expressed the most:
riddle_26.png

riddle_26_b.png

(in other words, those are the places where the molecule is present in abundance). The data were obtained with the help of Metabolic gEne RApid Visualizer

"Edited"

The molecule plays an important role in wound healing (it helps to form a blood clot and protect the tissue), as well as in cell growth, migration, differentiation, and maintenance of cell shape.

Rules

This contest lasts for 6 days.

Leave your guess (1 guess only (not 2 or 3+)) in the comments section of the post.

Don’t edit your comment/Don't delete or add new comments with the answers and don’t provide any evidence that your answer is correct.

I’ll provide the answer in the comments section of the next post on the 7th day of the week’s stage.

The first user with correct answer is the winner.

Some of the clues have already been provided in the post.

Additional clues will be given Wednesday (20:00 ± 15 minutes UTC) (I’ll update this post).

The reason is that some people might need less information to make conclusions that the others.

Additional clues will be added at the end of the "Riddle" section before the "Rules" section with "Edited" label.

The winner will be announced on Friday, May 29, 2020, 20:00 ± 15 minutes UTC in the comments section of the next post. Plus I’ll publish a detailed review of the riddle after a while.

I’ll transfer the tokens (STEM + Hive + TMN + CCC + PAL) (if the winner provides me his/her NEO-address) to the winner on that day and add the transaction ID in the comments section.

I’m planning to run this contest every week.
So, you should expect to see the 1st week’s riddle for June on Saturday, May 30, 2020, 20:00 ± 15 minutes UTC.

References

I’ll add all the references for this post later, because most of them contain the name of the molecule.
That would be a spoiler.
I’ll add them after a while.

Important

This contest is the work in progress.
A lot can be changed in the future.
Any recommendations/suggestions are very welcome.
If you have any questions, feel free to ask them in the comments section.

All images (without the license specified) are used under the doctrine known in USA as "Fair Use" (similar doctrines are used in other countries). For more information visit the US Gov website

Sort:  

Fibronectin
:)

"Fibronectin"
you're right.
congrats!
just sent you 10 Hive / 200 STEM / 200 CCC / 200 PAL

https://hiveblocks.com/tx/f1585997e6cd26edb7b0a6deda4add786691484d

https://he.dtools.dev/@alexbiojs

and 400 TMN to the NEO-address you provided me earlier
(AVqposYkBfWBWi8Ex9ztw4utGnF7C7sgGf)

https://peakd.com/hive-163521/@alexbiojs/identify-the-molecule-league-20-prize-knowledge-5-hive-100-stem-200-tmn
("Identify the molecule" league #20. Prize: knowledge + 5 Hive + 100 STEM + 200 TMN)

Transaction ID: 8121d35077bb1517b3dcc2c6a29366eba70ccdf30b8f35fa83453f75fc18d705
https://neoscan.io/transaction/8121D35077BB1517B3DCC2C6A29366EBA70CCDF30B8F35FA83453F75FC18D705

thanks for your interest for this contest/league.

please note,
there will be no this contest this week/today.
the contest will re-start next Saturday

I can't wait! I'll try my best. :)

I think it could be Fibrinogen (but the 11th letter is missing so I'm not sure)!

!discovery 30

Fibronectin is the right answer
https://en.wikipedia.org/wiki/Fibronectin
you were very close to the right answer.
thanks for your interest for this contest/league.

Oh!! :) it doesn't matter! Thank you for the great initative, have a nice day!

forgot to say,
there will be no this contest this week/today.
the contest will re-start next Saturday

 4 months ago Reveal Comment
 4 months ago Reveal Comment