The Ultimate Guide to Cannabinoids & Terpenes for Pain Relief
Cannabis has been used for centuries as a natural remedy for pain. With growing interest in hemp-derived products like CBD (cannabidiol), people are exploring alternative ways to manage discomfort through plant-based compounds. Cannabinoids and terpenes are two key elements found in cannabis and hemp that contribute to these pain-relieving properties. In this guide, we’ll focus on non-psychoactive cannabinoids such as CBD and CBG, alongside terpenes, and explore how they work to alleviate pain. We’ll also cover the best methods of consumption, from topicals to ingestibles and vaping.
What Are Cannabinoids?
Cannabinoids are chemical compounds found in hemp and cannabis plants that interact with the body’s endocannabinoid system (ECS). This system helps regulate several physiological processes like pain, mood, and inflammation. While THC (tetrahydrocannabinol) is the most well-known cannabinoid, we’ll focus on non-psychoactive cannabinoids, such as CBD (cannabidiol), CBG (cannabigerol), and CBN (cannabinol), which are widely used for pain relief without producing a "high."
CBD (Cannabidiol)
CBD is one of the most abundant cannabinoids in hemp plants and is praised for its anti-inflammatory and analgesic (pain-relieving) properties. It interacts with the body by influencing receptors involved in pain signaling, particularly the TRPV1 receptors, which modulate pain perception. Additionally, CBD can help reduce inflammation by lowering the production of pro-inflammatory molecules called cytokines. CBD is a popular option for those seeking pain relief without psychoactive effects, making it suitable for a wide range of users, including athletes and seniors.CBG (Cannabigerol)
Often referred to as the "mother of all cannabinoids," CBG serves as the precursor to other cannabinoids like CBD and THC. Early research suggests that CBG has anti-inflammatory and analgesic properties, which can be particularly beneficial for conditions like inflammatory bowel disease (IBD) and other inflammatory pain disorders. Like CBD, CBG is non-intoxicating and offers a clear-headed option for pain relief.CBN (Cannabinol)
CBN is mildly psychoactive, but not to the extent of THC. It is often praised for its sedative properties, which can be helpful for people with muscle pain and discomfort that interferes with sleep. CBN is also being studied for its potential in relieving chronic pain, making it a useful option in full-spectrum CBD products that contain trace amounts of this cannabinoid.
What Are Terpenes?
Terpenes are the aromatic compounds responsible for the unique scents of cannabis and hemp strains. Beyond their aromas, terpenes possess therapeutic effects and can significantly enhance the pain-relieving properties of cannabinoids through the entourage effect. This synergy between cannabinoids and terpenes amplifies their overall benefits.
Here are a few terpenes commonly found in hemp that can aid with pain relief:
Myrcene
Myrcene, often found in hemp and other plants like hops, is known for its sedative and muscle-relaxing effects. Research suggests that it also has analgesic properties, making it useful for managing chronic pain. Strains with high myrcene content can be especially calming, which is beneficial for both pain and stress relief.Limonene
Limonene, a citrus-scented terpene, offers anti-inflammatory and mood-enhancing benefits. Its ability to reduce stress and anxiety can indirectly help people coping with pain, especially chronic conditions that are exacerbated by emotional distress.Caryophyllene
Caryophyllene stands out because it is a terpene that also acts like a cannabinoid by directly interacting with CB2 receptors in the ECS, which are linked to reducing inflammation. It has been shown to help with conditions like arthritis and neuropathic pain.Linalool
Linalool, known for its floral scent (commonly found in lavender), has anti-inflammatory and analgesic effects. It can be particularly helpful for managing pain associated with arthritis or muscle soreness.
How Cannabinoids and Terpenes Work Together: The Entourage Effect
When cannabinoids and terpenes work together, they create an enhanced therapeutic effect known as the entourage effect. For pain relief, full-spectrum hemp products, which include a variety of cannabinoids and terpenes, may offer more significant relief than CBD alone. By using a combination of cannabinoids like CBD, CBG, and CBN alongside terpenes such as myrcene or caryophyllene, these products can target multiple pathways involved in pain and inflammation.
Methods of Using Hemp-Derived Products for Pain Relief
Cannabinoids and terpenes can be consumed in a variety of ways, each offering unique benefits depending on your pain management needs. Here, we’ll explore the three most popular methods: topical application, internal consumption, and smoking/vaping.
Topical Use (Creams, Lotions, Balms)
Topical CBD products, such as creams, balms, and lotions, are applied directly to the skin and work by interacting with localized cannabinoid receptors. These products are ideal for treating muscle pain, joint discomfort, and inflammation. Topical use allows for targeted relief, making it a popular choice for people suffering from arthritis or post-workout soreness. Unlike ingestible CBD, topicals don’t enter the bloodstream, so you won’t experience full-body effects. This makes them a convenient option for localized pain relief without affecting your mental clarity or energy levels.Internal Consumption (Edibles, Tinctures, Capsules)
Ingesting cannabinoids through edibles, tinctures, or capsules is another effective way to relieve pain. When consumed internally, CBD and other cannabinoids travel through the digestive system before entering the bloodstream, providing more widespread and longer-lasting relief.- Tinctures offer flexibility in dosing and are usually absorbed under the tongue (sublingually) for faster effects.
- Edibles and capsules are convenient but can take longer to kick in, as they must be processed by the digestive system. However, the effects tend to last longer, making these forms ideal for managing chronic pain over extended periods.
Smoking and Vaping
Inhaling cannabinoids through smoking or vaping provides almost immediate relief, making this method ideal for those dealing with acute pain or sudden flare-ups. When cannabinoids are inhaled, they enter the bloodstream quickly through the lungs, allowing for faster onset compared to edibles.- Vaping CBD is considered a healthier alternative to smoking, as it avoids the combustion process. There are many CBD vape products available that offer a quick and effective way to manage pain without harmful byproducts like tar.
Conclusion
Hemp-derived cannabinoids and terpenes offer promising natural solutions for pain relief without the psychoactive effects of THC. Whether you’re looking for localized relief through topical creams or seeking longer-lasting effects through ingestibles, there is a wide variety of methods to fit your needs. By exploring different combinations of cannabinoids like CBD, CBG, and CBN, alongside terpenes such as myrcene and caryophyllene, you can tailor your approach to pain management and find a method that works best for you.
Remember, as with any supplement, consult with a healthcare professional before adding CBD or other hemp-derived products to your routine, especially if you’re managing chronic pain or are on other medications.
Sources:
- Russo, E. B. (2016). “Beyond Cannabis: Plants and the Endocannabinoid System.” Trends in Pharmacological Sciences.
- Borrelli, F., et al. (2013). “Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats.” Cannabis and Cannabinoid Research.
- Baron, E. P. (2018). “Medicinal Properties of Terpenes Found in Cannabis.” Pain Medicine.
- Chen, H., et al. (2019). “Anticancer, Anti-Inflammatory, and Antioxidant Activities of Limonene.” European Journal of Pharmacology.
- Linck, V. M., et al. (2009). “Inhaled Linalool-Induced Sedation in Mice.” Phytomedicine.
- Gallily, R., et al. (2015). “CBD/THC Synergistic Interactions in Pain Reduction.” Journal of Pharmacology.
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